Neuro-cutaneous Melanosis

Diffuse Cutaneous Melanosis Associated with Malignant Melanoma.

780 Ann Dermatol Received December 10, 2014, Revised February 7, 2015, Accepted for publication February 18, 2015 Corresponding author: Joanna Mangana, Department of Dermatology, University Hospital Zurich, Gloriastrasse 31, CH 8091, Zurich, Switzerland. Tel: 41-44-255-3155, Fax: 41-44-255-454, E-mail: johanna. mangana@ usz.ch This is an Open Access article distributed under the terms of the Cr...

Diffuse cutaneous melanosis: rare complication of metastatic melanoma*

Diffuse cutaneous melanosis is a rare complication of metastatic melanoma related to a worse prognosis. There are few cases reported in the literature. Its pathogenesis has not been completely elucidated, although studies have suggested certain mechanisms for its occurrence. It is clinically manifested as a blue-gray discoloration of the skin and mucous membranes in a cephalo caudal progression...

On Melanosis

Melanosis coli.

n engl j med 368;24 nejm.org june 13, 2013 2303 A 50-year-old woman underwent colonoscopy for rectal bleeding. Her entire colon appeared dark brown and black, a finding consistent with the diagnosis of melanosis coli (Panel A). Random biopsy specimens from the descending colon revealed sheets and clusters of macrophages laden with brownish pigment in the lamina propria (Panel B, arrow). A tiny,...

Syphilitic Melanosis

Sir,?I am referring to a paper 'on p. 172 of the Indian Medical Gazette, April 1944, on 'Syphilitic melanoderma' where ycm state that in Becher and Obermayer no mention is made of syphilis as a cause of melanosis. In my book ' Histologie der Hautkrankheiten' Springer Verlag, Berlin 1925, Vol. I, p. 517, I do mention it and refer to Fourrier and to Unna as describing it as a rare type of the dis...